منابع مشابه
Molecular Mechanisms of Antipsychotic Drug-Induced Diabetes
Antipsychotic drugs (APDs) are widely prescribed to control various mental disorders. As mental disorders are chronic diseases, these drugs are often used over a life-time. However, APDs can cause serious glucometabolic side-effects including type 2 diabetes and hyperglycaemic emergency, leading to medication non-compliance. At present, there is no effective approach to overcome these side-effe...
متن کاملIntrinsic and Antipsychotic Drug-Induced Metabolic Dysfunction in Schizophrenia
For decades, there have been observations demonstrating significant metabolic disturbances in people with schizophrenia including clinically relevant weight gain, hypertension, and disturbances in glucose and lipid homeostasis. Many of these findings pre-date the use of antipsychotic drugs (APDs) which on their own are also strongly associated with metabolic side effects. The combination of APD...
متن کاملAntipsychotic drug overdose.
EMERGENCY nurse 17 Antipsychotic drugs (or neuroleptics) are a large class of drugs which can be divided into three groups: phenothiazine, miscellaneous and atypical (Box 1). They are used to tranquillise patients without impairing consciousness and without causing paradoxical excitement. They are often referred to as major tranquillisers but this is misleading since these drugs also relieve fl...
متن کاملIs neuroleptic dysphoria a variant of drug-induced extrapyramidal side effects?
OBJECTIVES Neuroleptic drugs induce psychological side effects such as dysphoria, cognitive impairment, and loss of motivation. These side effects were largely underrecognized and trivialized in the past as variants of extrapyramidal side effects (EPSEs). We review the recent literature on the subject and clarify the relation between neuroleptic-induced dysphoria and EPSEs. METHODS We critica...
متن کاملAntipsychotic-induced hyperprolactinemia.
Use of antipsychotic agents has been associated with hyperprolactinemia, or elevated prolactin levels; this hormonal abnormality can interfere with the functioning of reproductive, endocrine, and metabolic systems. As antipsychotic agents are increasingly used for both United States Food and Drug Administration-approved and nonapproved indications, many individuals are at risk for developing an...
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ژورنال
عنوان ژورنال: British Journal of Psychiatry
سال: 1996
ISSN: 0007-1250,1472-1465
DOI: 10.1192/bjp.169.4.524b